Biodegradable Temperature- and pH Dually-responsive Poly(β-amino ester)
نویسندگان
چکیده
منابع مشابه
Esterase- and pH-responsive poly(β-amino ester)-capped mesoporous silica nanoparticles for drug delivery.
Gating of mesoporous silica nanoparticles (MSNs) with the stimuli-responsive poly(β-amino ester) has been achieved. This hybrid nanocarrier releases doxorubicin (DOX) under acidic conditions or in the presence of porcine liver esterase. The DOX loaded poly(β-amino ester)-capped MSNs reduce cell viability when tested on MDA-MB-231 human breast cancer cells.
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ژورنال
عنوان ژورنال: DEStech Transactions on Engineering and Technology Research
سال: 2017
ISSN: 2475-885X
DOI: 10.12783/dtetr/apetc2017/11404